Chin. J. Org. Chem. ›› 2003, Vol. 23 ›› Issue (11): 1244-1248. Previous Articles     Next Articles

微波促进的1,3-偶极环加成4β-1,2,3-三唑鬼臼毒素的合成

施建峰;王彦广   

  1. 浙江大学化学系
  • 发布日期:2003-11-25

Solvent-Free Synthesis of 4β-1,2,3-Triazol-1-ylpodophyllotoxins by Microwave-Induced 1,3-Dipolar Cycloaddition of Azides to Alkynes

Shi Jianfeng;Wang Yanguang   

  1. Department of Chemistry, Zhejiang University
  • Published:2003-11-25

1, 3-Dipolar cydoaddition of 4β-azidopodophyllotoxins 4 to alkynes under solvent-free microwave irradiation resulted in the corresponding 4β-1,2,3-triazol-l-yl podophy Ho toxins 6~7 in good to excellent yields. The structures of compounds were confirmed by IR, ~1H NMR and MS spectra as well as elemental analysis.

Key words: PYRRODIAZOLE P;CYCLOADDITION REACTION;podophyllotoxin;IR;1HNMR, MS

CLC Number: