A series of new 9-hydroxy-9-xanthenecarboxylates were designed and synthesized. In the synthesis of the tricyclic group, the preparation of disubstituted xanthene derivatives was studied. In the synthesis of the amino alcohol, the 10% Pd/C was used as the catalysts, the pressure was dropped to 30 kg/cm2, the conditions for hydrogenation reactions were optimized, and the yield of the reaction was increased. For the synthesis of target compounds, the post-treatment and purification methods were improved and at the same time, the procedures were simplified.

Key words: hydroxycarboxylate, methyl 9-hydroxyl-9-xanthenecarboxylate, amino alcoh, xanthene