Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (06): 985-988. Previous Articles     Next Articles

Reports

由邻硝基苯胺一锅法合成苯并咪唑化合物

毛郑州; 汪朝阳*; 宋秀美; 莫阳青   

  1. (华南师范大学化学与环境学院 广州 510006)
  • 收稿日期:2008-06-15 修回日期:2008-12-20 发布日期:2009-06-20
  • 通讯作者: 汪朝阳

One-Pot Synthesis of Benzimidazoles from o-Nitroaniline

Mao, Zhengzhou ; Wang, Zhaoyang*; Song, Xiumei ; Mo, Yangqing   

  1. (School of Chemistry and Environment, South China Normal University, Guangzhou 510006)
  • Received:2008-06-15 Revised:2008-12-20 Published:2009-06-20
  • Contact: Wang, Zhaoyang

Using o-nitroaniline as the starting material, benzimidazoles were prepared by the way of one-pot synthesis in the system of SnCl2•2H2O/KI/HCl at the temperature of 100 ℃. The new method might be a convenient route to benzimidazoles for its adventages of simple operation, mild condition, high yield, available catalyst and water usage as solvent.

Key words: one-pot synthesis, benzimidazole, o-nitroaniline