Chin. J. Org. Chem. ›› 1990, Vol. 10 ›› Issue (5): 440-444. Previous Articles     Next Articles

Original Articles

E-和Z-α-取代肉杜酰哌嗪类的合成及其光异构化反应

李安良;林强;刘维勤   

  1. 北京医科大学药学院
  • 发布日期:1990-10-25

Synthesis of E-and Z-α-substituted cinnamoyl piperazines and their photoisomerization

LI ANLIANG;LIN QIANG;LIU WEIQIN   

  • Published:1990-10-25

Introduction of Me, Ph, acetylamino, or benzoylamino groups to the a-position of 4-(3,4,5-trimethoxycinnamoyl)-1-(pyrrolidinocarbonylmethyl)piperazine (I) gave a series of a-substituted cinnamoyl piperazines, which was photoisomerized under the irradiation of sun light, tungsten-halogen lamp, or mercury lamp. The configurations of the products were assigned with 1H NMR and UV.

Key words: PIPERAZINE P, ULTRAVIOLET SPECTROPHOTOMETRY, PHOTOCHEMICAL REACTION, NMR SPECTROMETRY, ELECTRICAL PROPERTIES, HIGH SPEED LIQUID CHROMATOGRAPHY, METHYL GROUP, HYDROPHOBILITY, STERIC EFFECT, ISOMERIZATION REACTION

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