A facile method for the debromination of a-bromocarbonyl compounds with dibutyl telluride

Abstract

Reductive debromination of a-bromo carbonyl compounds with di-Bu telluride is described. Debromination was greatly enhanced by organic bases such as Et3N, or pyridine and the reaction in acetonitrile might occur even at room temperature Thus, reaction of RCOCH2Br(R = Ph, p-BrC6H4, 2-furyl, 2-thienyl, Me) with Bu2Te in presence of Et3N gave 86-92% RCOMe.

Key words: PYRIDINE, BROMINE COMPOUNDS, TETRAHYDROFURAN, DEHALOGENATION REACTION, DIBUTYL P, TRIETHYL AMINE, CARBONYL COMPOUNDS, TELLURIUM COMPOUNDS, ACETONITRILE

CLC Number:

O621

Cite this article

ZHONG QI;MA FENG;LIU CHANGQING;SHAO JIANGUO. A facile method for the debromination of a-bromocarbonyl compounds with dibutyl telluride[J]. Chin. J. Org. Chem., 1991, 11(2): 209-213.

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