Chin. J. Org. Chem. ›› 2000, Vol. 20 ›› Issue (3): 299-305. Previous Articles     Next Articles

非蛋白氨基酸对生物活性多肽的修饰及其构效关系的研究进展

闫爱新;田桂玲;叶蕴华   

  1. 北京大学化学与分子工程学院
  • 发布日期:2000-06-25

Progress in modification of bioactive peptides with non-protein amino acids and their application in the studies of structure- activity relationship

Yan Aixin;Tian Guiling;Ye Yunhua   

  • Published:2000-06-25

The diversity of structure and physiological activity of non-protein amino acids is briefly described. Some peptides containing non- protein amino acid residues are introduced and the essential roles of these residues are discussed. Recent progress in modifying the bioactive peptides with non-protein amino acids and their preferences are generally reviewed.

Key words: NON-PROTEIN AMINO ACID, POLYPEPTIDE, BIOACTIVE SUBSTANCE, STRUCTURE ACTIVITY RELATIONSHIP, MODIFICATION, ANTAGONIST, KINETIN

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