Synthesis and Herbicidal Activity of 2-Cyano-3-(2-fluoropyrid-5-yl)- methylamino-3-methylthioacrylates

Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (03): 337-340. Previous Articles Next Articles

Original Articles

2-氰基-3-(2-氟吡啶-5-基)甲氨基-3-甲硫基氰基丙烯酸酯类化合物的合成及除草活性

邹小毛，郁丽敏，高颍，施欢乐，裴江，刘斌
李慧芬，胡方中，杨华铮^*

(南开大学元素有机化学国家重点实验室元素有机化学研究所天津 300071)

收稿日期:2005-01-30 修回日期:2005-09-28 发布日期:2006-02-28
通讯作者: 杨华铮

Synthesis and Herbicidal Activity of 2-Cyano-3-(2-fluoropyrid-5-yl)- methylamino-3-methylthioacrylates

ZOU Xiao-Mao,YU Li-Min,GAO Yin,SHI Huan-Le,PEI Jiang,LIU Bin
LI Hui-Fen,HU Fang-Zhong,YANG Hua-Zheng*

(State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-organic Chemistry,
Nankai University, Tianjin 300071)

Received:2005-01-30 Revised:2005-09-28 Published:2006-02-28
Contact: YANG Hua-Zheng

Abstract

A series of 2-cyano-3-(2-fluoropyrid-5-yl)methylamino-3-methylthioacrylates were synthesized as herbicidal inhibitors of photosynthesis II electron transport and some of these compounds exhibited good herbicidal activities. A suitable group at the 3-position of acrylate is essential for high herbicidal activity. 2-Cyanoacrylates containing a 2-fluoro-5-pyridyl group may be provided higher herbicidal activities than relevant chloride derivatives.

Key words: herbicidal activity, SAR, 2-cyano-3-(2-fluoropyrid-5-yl)methylamino-3- methylthioacrylate, inhibitor of photosynthesis II electron transport

Cite this article

ZOU Xiao-Mao,YU Li-Min,GAO Yin,SHI Huan-Le,PEI Jiang,LIU Bin
LI Hui-Fen,HU Fang-Zhong,YANG Hua-Zheng*. Synthesis and Herbicidal Activity of 2-Cyano-3-(2-fluoropyrid-5-yl)- methylamino-3-methylthioacrylates[J]. Chin. J. Org. Chem., 2006, 26(03): 337-340.

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2-氰基-3-(2-氟吡啶-5-基)甲氨基-3-甲硫基氰基丙烯酸酯类化合物的合成及除草活性

Synthesis and Herbicidal Activity of 2-Cyano-3-(2-fluoropyrid-5-yl)- methylamino-3-methylthioacrylates

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