Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (04): 432-437. Previous Articles     Next Articles

Original Articles

[1-芳基甲羰基-2-(1,2,4-三唑-1-基)]乙基-N,N-二烷基二硫代氨基甲酸酯衍生物的合成、结构表征及生物活性研究

建方方*,许良忠,文丽荣,朱崇毅   

  1. (青岛科技大学新材料和功能配合物实验室 青岛 266042)
  • 收稿日期:2004-04-05 修回日期:2004-11-10 发布日期:2005-03-30
  • 通讯作者: 建方方

Synthesis, Structure Characterization and Biological Activities of Aromatic Triazole Compounds Containing N,N-Dialkyldithiocarbamate

JIAN Fang-Fang*,XU Liang-Zhong,WEN Li-Rong,ZHU Chong-Yi   

  1. (New Materials & Function Coordination Chemistry Laboratory, Qingdao University of
    Science and Technology, Qingdao 266042)
  • Received:2004-04-05 Revised:2004-11-10 Published:2005-03-30
  • Contact: JIAN Fang-Fang

Five novel 1,2,4-triazole compounds containing N,N-dialkyldithiocarbamate moiety were designed and synthesized. Their structures were identified by means of elemental analysis, IR, 1H NMR and MS spectra. The crystal structure of [α-(4-methoxyphenylcarbonyl)-2-(1,2,4-triazol-1-yl)]ethyl-N,N-dime- thyldithio-carbamate was determined by single-crystal X-ray diffraction analysis. It crystallizes in triclinic system with space group , a=0.73482(15) nm, b=1.1051(2) nm, c=1.1209(2) nm, α=90.32(3)°, β=101.97(3)°, γ=105.13(3)°, V=0.8578(3) nm3, Z=2, Dc=1.357 g/cm3, F(000)=368, µ=0.324 mm-1. The result of the biological test showed that the five compounds all have fungicidal and plant growth-regulating activities.

Key words: N,N-dialkyldithiocarbamate, crystal structure, biological ac-tivity, 1,2,4-triazole