Progress in Preparation of β,β-Difluorovinyl Compounds

doi:10.6023/cjoc1104113

Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (04): 661-666.DOI: 10.6023/cjoc1104113 Previous Articles Next Articles

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β,β-二氟乙烯基化合物制备方法研究进展

刘运, 邓萌萌, 张智勇, 丁肖华, 戴志群, 关金涛

武汉工业学院化学与环境工程学院武汉 430023

收稿日期:2011-04-11 修回日期:2011-09-19 发布日期:2012-04-24
通讯作者: 张智勇 E-mail:zzy6211@126.com, zzy6211@yahoo.com.cn
基金资助:
国家自然科学基金(No. 60736)、湖北省自然科学基金(No. 2007ABA279)、湖北省教育厅科技基金(No. Z0091801)、武汉工业学院研究生教育创新计划(No. 09cx19)资助项目.

Progress in Preparation of β,β-Difluorovinyl Compounds

Liu Yun, Deng Mengmeng, Zhang Zhiyong, Ding Xiaohua, Dai Zhiqun, Guan Jintao

Department of Chemistry and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023

Received:2011-04-11 Revised:2011-09-19 Published:2012-04-24
Supported by:
Project supported by the National Natural Science Foundation of China (No. 60736), the Natural Science Foundation of Hubei Province of China (No. 2007ABA279), the Scientific Research Fund of Hubei Provincial Education Department (No. Z0091801), and the Educational and Innovative Foundation for the Graduate Students of Wuhan Polytechnic University (No. 09cx19).

Numerous methods for the preparation of β,β-difluorovinyl compounds have been reported with the widely application of difluoroethenes recently. In this paper, an overview on the progress of synthetic methods of β,β-difluorovinyl compounds, based on halodifluroacetate, halodifluoromethane, bi-sphosphonium salts, metal-assisted, double-trifluoromethyl mercury, LDA and difluormethyl aromatic sulfone, has been introduced. And the relevant reaction mechanisms are also proposed and explained.

Key words: difluoroethylene, Wittig reaction, phosphorus ylide

Cite this article

Liu Yun, Deng Mengmeng, Zhang Zhiyong, Ding Xiaohua, Dai Zhiqun, Guan Jintao. Progress in Preparation of β,β-Difluorovinyl Compounds[J]. Chin. J. Org. Chem., 2012, 32(04): 661-666.

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β,β-二氟乙烯基化合物制备方法研究进展

Progress in Preparation of β,β-Difluorovinyl Compounds

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