Synthesis of 1,7-Diarylhepta-1,6-diyne Compounds

doi:10.6023/cjoc201408021

Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (3): 735-738.DOI: 10.6023/cjoc201408021 Previous Articles Next Articles

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1,7-二芳基-1,6-庚二炔化合物的合成

温燕梅, 谢建英, 冯润光, 黄绪明

广东海洋大学理学院湛江 524088

收稿日期:2014-08-20 修回日期:2014-10-16 发布日期:2014-11-13
通讯作者: 温燕梅 E-mail:wym1503@163.com
基金资助:
国家自然科学基金(No. 21172076)资助项目.

Synthesis of 1,7-Diarylhepta-1,6-diyne Compounds

Wen Yanmei, Xie Jianying, Feng Runguang, Huang Xuming

College of Science, Guangdong Ocean University, Zhanjiang 524088

Received:2014-08-20 Revised:2014-10-16 Published:2014-11-13
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21172076).

1. Synthesis of 1,7-Diarylhepta-1,6-diyne Compounds.PDF(659KB)

Abstract

Hepta-1,6-diynes are very useful synthetic intermediates. Using PdCl₂/CuI as the catalyst and NEt₃ as the base in tetrahedrofuran, ten 1,7-diarylhepta-1,6-diynes were synthesized by a simple Sonogashira coupling reaction of terminal diacetylenes and aryl halides. It is also indicated that 1,8-diiodonaphthalene can undergo the same transformation to 1,8-　bis(phenylethynyl)naphthalene under typical conditions. Moreover, the structures of hepta-1,6-diyne derivatives were confirmed by ¹H NMR, ¹³C NMR, IR and MS techniques.

Key words: Palladium-catalyzed, Hepta-1,6-diyne, Sonogashira reaction

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Wen Yanmei, Xie Jianying, Feng Runguang, Huang Xuming. Synthesis of 1,7-Diarylhepta-1,6-diyne Compounds[J]. Chin. J. Org. Chem., 2015, 35(3): 735-738.

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1,7-二芳基-1,6-庚二炔化合物的合成

Synthesis of 1,7-Diarylhepta-1,6-diyne Compounds

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