Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (11): 2347-2357.DOI: 10.6023/cjoc201504047 Previous Articles     Next Articles



张艺扬, 穆博帅, 李媛   

  1. 河北师范大学化学与材料科学学院 石家庄 050024
  • 收稿日期:2015-04-30 修回日期:2015-07-06 发布日期:2015-07-10
  • 通讯作者: 李媛
  • 基金资助:

    国家自然科学基金(No. 20972040)资助项目.

Michael Addition and Tandem Reaction of Aminothiphenols with α,β- Unsaturated Ketones with High Steric Hindrance Catalyzed by CeCl3·7H2O-NaI Supported on SiO2 Microsphere

Zhang Yiyang, Mu Boshuai, Li Yuan   

  1. College of Chemistry and Material Science, Hebei Normal University, Shijiazhuang 050024
  • Received:2015-04-30 Revised:2015-07-06 Published:2015-07-10
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 20972040).

Using SiO2 microsphere with size of 5 μm as support, CeCl3·7H2O-NaI/SiO2 supported catalyst was prepared and characterized by SEM, EDS and XDR techniques and its catalytic performance for Michael addition and tandem Michael addition/condensation reactions between aminothiophenols and α,β-unsaturated ketones with high steric hindrance were investigated. The experimental results showed that CeCl3·7H2O-NaI/SiO2 can catalyzed above reactions in moderate to good yields. When the catalyst was used fifth times, its morphology was largely unchanged, but its catalytic activity decreased for losing of small amounts of metal cerium in the process of catalyzing. It was also found that CeCl3·7H2O-NaI/SiO2 can catalyze both the Michael addition of aminothiophenols to α,β-unsaturated ketones and the condensation reaction between ketones and amines.

Key words: Michael addition, tandem reaction, CeCl3·, 7H2O-NaI, SiO2 microsphere, supported catalyst