Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (3): 586-602.DOI: 10.6023/cjoc201609030 Previous Articles     Next Articles

REVIEW

氧气参与的无张力碳-碳单键断裂反应研究进展

吴空, 宋婵, 崔冬梅   

  1. 浙江工业大学药学院 杭州 310014
  • 收稿日期:2016-09-28 修回日期:2016-10-28 发布日期:2016-11-17
  • 通讯作者: 崔冬梅,E-mail:cuidongmei@zjut.edu.cn E-mail:cuidongmei@zjut.edu.cn

Advances of Unstrained Carbon-Carbon Single Bond Cleavage with Oxygen

Wu Kong, Song Chan, Cui Dongmei   

  1. College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014
  • Received:2016-09-28 Revised:2016-10-28 Published:2016-11-17
  • Contact: 10.6023/cjoc201609030 E-mail:cuidongmei@zjut.edu.cn

Unstrained carbon-carbon single bonds are ubiquitous in organic compounds, the cleavage of this bond is one of the most significant and challenging subject in organic chemistry. Oxidative cleavage of unstrained carbon-carbon single bond has become a great tendency, in particular, the transition metal-catalyzed oxidative cleavage reaction, which had made significant progress in recent years. Oxygen, as the most inexpensive and environmentally friendly oxidant, has been widely used in various organic reactions. This review is an overview of recent advances of unstrained carbon-carbon single bond cleavage with oxygen according to whether transition metal catalysis is needed.

Key words: oxygen, unstrained carbon-carbon single bond, cleavage