Brønsted Acid-Promoted the Synthesis of Furo[2,3-b]quinolines

doi:10.6023/cjoc201612032

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (7): 1824-1829.DOI: 10.6023/cjoc201612032 Previous Articles Next Articles

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布朗斯特酸促进的呋喃[2,3-b]喹啉类并环化合物的合成

张志国, 郑丹, 麻娜娜, 毕晶晶

河南师范大学化学化工学院新乡 453007

收稿日期:2016-12-08 修回日期:2017-01-19 发布日期:2017-03-03
通讯作者: 张志国 E-mail:zhangzg@htu.edu.cn
基金资助:
国家自然科学基金（Nos.21272057，21372065）、河南省高等学校青年骨干教师资助计划（No.2014GGJS-049）、河南省教育厅重点研究（Nos.14A150019，14B150042，15A150015）、河南省高校科技创新人才支持计划（No.17HASTIT002）、河南师范大学杰出青年人才培育基金（No.14YR002）资助项目.

Brønsted Acid-Promoted the Synthesis of Furo[2,3-b]quinolines

Zhang Zhiguo, Zheng Dan, Ma Na'na, Bi Jingjing

School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007

Received:2016-12-08 Revised:2017-01-19 Published:2017-03-03
Contact: 10.6023/cjoc201612032 E-mail:zhangzg@htu.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Nos.21272057,21372065),the Young Backbone Teachers Fund of Henan Province (No.2014GGJS-049),the Key Project of Henan Provincal Educational Committee (Nos.14A150019,14B150042,15A150015),the Science&Technology Innovation Talents in Universities of Henan Province (No.17HASTIT002),and the Outstanding Young Talent Cultivation Project Funding of Henan Normal University (No.14YR002).

1. Brønsted Acid-Promoted the Synthesis of Furo[2,3-b]quinolines.PDF(803KB)

Abstract

The furoquinoline unit is present in many natural products. Here, an approach is presented for the preparing of furo[2,3-b]quinolines from readily available multi-substituted furans in the presence of Brønsted acid via an intramolecular cyclization under the heating conditions. Simple operation, good compatibility, high regioselectivity and morderate yields are the advantages of the method.

Key words: Brø, nsted acid, furo[2,3-b]quinoline, trifluoromethanesulfonic acid, Friedel-Crafts reaction

Cite this article

Zhang Zhiguo, Zheng Dan, Ma Na'na, Bi Jingjing. Brønsted Acid-Promoted the Synthesis of Furo[2,3-b]quinolines[J]. Chin. J. Org. Chem., 2017, 37(7): 1824-1829.

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布朗斯特酸促进的呋喃[2,3-b]喹啉类并环化合物的合成

Brønsted Acid-Promoted the Synthesis of Furo[2,3-b]quinolines

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