Carbazolation Study of Active Arenes with Carbazole-Containing Hypervalent Iodine(III) Reagents

doi:10.6023/cjoc201905050

Chinese Journal of Organic Chemistry ›› 2019, Vol. 39 ›› Issue (8): 2166-2174.DOI: 10.6023/cjoc201905050 Previous Articles Next Articles

Special Issue: 陈茹玉先生诞辰100周年；碳氢活化合辑2018-2019；元素有机化学合辑2018-2019

Articles

咔唑基高价碘试剂参与的活化芳烃直接咔唑化反应研究

兰天磊^a,b, 张越^a,b, 刘伟^c, 席婵娟^a, 陈超^a

a 清华大学化学系生命有机磷化学及化学生物学教育部重点实验室北京 100084;
b 天津科技大学化工与材料学院天津 300457;
c 天津科技大学理学院天津 300457

收稿日期:2019-05-28 修回日期:2019-07-12 发布日期:2019-07-17
通讯作者: 陈超 E-mail:chenchao01@mails.tsinghua.edu.cn
基金资助:
国家重点研发计划（No.2016YFB0401400）、国家自然科学基金（Nos.21302139，21672120，21871158）和霍英东青年教师基金（No.151014）资助项目.

Carbazolation Study of Active Arenes with Carbazole-Containing Hypervalent Iodine(III) Reagents

Lan Tianlei^a,b, Zhang Yue^a,b, Liu Wei^c, Xi Chanjuan^a, Chen Chao^a

a Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084;
b College of Chemical Engineering and Materials Science, Tianjin University of Science & Technology, Tianjin 300457;
c College of Sciences, Tianjin University of Science & Technology, Tianjin 300457

Received:2019-05-28 Revised:2019-07-12 Published:2019-07-17
Contact: 10.6023/cjoc201905050 E-mail:chenchao01@mails.tsinghua.edu.cn
Supported by:
Project supported by the National Key Research and Development Program of China (No. 2016YFB0401400), the National Natural Science Foundation of China (Nos. 21302139, 21672120, 21871158) and the Fok Ying Tong Education Foundation of China (No. 151014).

1. Carbazolation Study of Active Arenes with Carbazole-Containing Hypervalent Iodine(III) Reagents.PDF(2085KB)

Abstract

Carbazole and its derivatives are widely used in the field of medicine and photoelectric materials. A kind of stable cyclic hypervalent iodine reagents containing carbazole group was developed, which belong to benziodoxole compounds. In the presence of Cu(I) catalyst, these reagents reacted with aromatic substrates to give N-aryl carbazole derivatives. The reaction conditions are mild and suitable for a variety of electron-rich arenes. And a radical mechanism was proposed.

Key words: carbazole, hypervalent iodine reagent, N-arylation, copper-catalysis

Cite this article

Lan Tianlei, Zhang Yue, Liu Wei, Xi Chanjuan, Chen Chao. Carbazolation Study of Active Arenes with Carbazole-Containing Hypervalent Iodine(III) Reagents[J]. Chinese Journal of Organic Chemistry, 2019, 39(8): 2166-2174.

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咔唑基高价碘试剂参与的活化芳烃直接咔唑化反应研究

Carbazolation Study of Active Arenes with Carbazole-Containing Hypervalent Iodine(III) Reagents

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