A Novel Phenanthroline-Based Fluorescent Probe for Pb(II)

doi:10.6023/cjoc202004037

Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (8): 2508-2512.DOI: 10.6023/cjoc202004037 Previous Articles Next Articles

一个基于菲咯啉的Pb(II)荧光探针

梅辉辉^a, 杨铭阳^b, 刘晓燕^a, 田玉平^a, 徐括喜^a

a 河南大学化学化工学院河南开封 475004;
b 河南大学民生学院河南开封 475004

收稿日期:2020-04-24 修回日期:2020-05-17 发布日期:2020-06-01
通讯作者: 田玉平, 徐括喜 E-mail:tianyuping@henu.edu.cn;xukx@henu.edu.cn
基金资助:
国家自然科学基金（No.31872311）资助项目.

A Novel Phenanthroline-Based Fluorescent Probe for Pb(II)

Mei Huihui^a, Yang Mingyang^b, Liu Xiaoyan^a, Tian Yuping^a, Xu Kuoxi^a

a College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004;
b Mingsheng College, Henan University, Kaifeng, Henan 475004

Received:2020-04-24 Revised:2020-05-17 Published:2020-06-01
Supported by:
Project supported by the Natural National Science Foundation of China (No. 31872311).

1. cjoc202004037.pdf(414KB)

Abstract

A novel fluorescent probe L for Pb²⁺ based phenanthroline derivative has been designed and synthesized. The probe L displayed fluorescence quenching emission excellent sensitivity specific toward Pb²⁺ ion. The introduction of Pb²⁺ resulted the quenching fluorescence of probe L and the color of the solution can be observed changes from yellow to orange in DMF-H₂O (V:V=1:1, 10 mmol/L Tris, pH=7.4). The detection limit was as low as 2.68×10^-7 mol/L. The bonding mechanism was confirmed by UV-vis, fluorescence, HRMS, ¹H NMR experiments and theoretical calculation. It was found that the probe had excellent reversibility for detection of Pb²⁺ and could be used to effectively identify Pb²⁺ in living cells.

Key words: phenanthroline derivative, fluorescent probe for Pb²⁺, living cell imaging

Cite this article

Mei Huihui, Yang Mingyang, Liu Xiaoyan, Tian Yuping, Xu Kuoxi. A Novel Phenanthroline-Based Fluorescent Probe for Pb(II)[J]. Chinese Journal of Organic Chemistry, 2020, 40(8): 2508-2512.

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一个基于菲咯啉的Pb(II)荧光探针

A Novel Phenanthroline-Based Fluorescent Probe for Pb(II)

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