Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (12): 4328-4331.DOI: 10.6023/cjoc202006034 Previous Articles     Next Articles

川芎内生菌Fusarium tricinctum的四个新吡喃-2-酮类成分

曹钰镁a, 旷歧轩a, 巨凤a, 邓赟a, 邓放a, 顾玉诚b, 任波a, 郭大乐a   

  1. a 成都中医药大学药学院 成都 611137;
    b Syngenta Jealott's Hill International Research Centre, Berkshire RG42 6EY, UK
  • 收稿日期:2020-06-18 修回日期:2020-07-19 发布日期:2020-08-11
  • 通讯作者: 任波, 郭大乐 E-mail:renbo@cdutcm.edu.cn;guodale@cdutcm.edu.cn
  • 基金资助:
    国家自然科学基金(No.81973460)、四川省科技厅(No.2018JY0186)及成都中医药大学杏林学者学科人才科研提升计划(No.BSH2018008)资助项目.

Four New 2-Pyrones from Fusarium tricinctum, an Endophytic Fungus of Ligusticum chuanxiong

Cao Yumeia, Kuang Qixuana, Ju Fenga, Deng Yuna, Deng Fanga, Gu Yuchengb, Ren Boa, Guo Dalea   

  1. a School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137;
    b Syngenta Jealott's Hill International Research Centre, Berkshire RG42 6EY, UK
  • Received:2020-06-18 Revised:2020-07-19 Published:2020-08-11
  • Supported by:
    Project supported by the National Natural Science Foundation of China (No. 81973460), the Foundation of Science and Technology Department of Sichuan Province (No. 2018JY0186) and the Xinglin Scholar Research Promotion Project of Chengdu University of Traditional Chinese Medicine (No. BSH2018008).

By silica gel, Sephadex LH-20 column chromatography as well as preparative high performance liquid chromatography (HPLC), four previously undescribed α-pyrones sharing same primary structure were isolated from the brown rice solid medium of Fusarium tricinctum. Their structures were elucidated by spectroscopic analyses and their absolute configurations were finally confirmed by a modified Snatzke's method.

Key words: 2-pyrone, Fusarium tricinctum, Ligusticum chuanxiong, induced circular dichroism