Notes

One-Pot Synthesis of 2-Amino-4-phenyl-6-(phenylsulfanyl)-3,5-dicyanopyridines in Ionic Liquids

  • TIAN Jin-Jin ,
  • GUO Hong-Yun
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  • College of Chemical Engineering and Material Science, Zhejiang University of Technology, Hangzhou 310014

Received date: 2011-05-13

  Revised date: 2011-09-03

  Online published: 2011-09-08

Abstract

The one-pot reaction of aldehydes, malononitrile and thiols was investigated in different medium. It was found that in ionic liquid [bmim]BF4 this reaction could be finished in short time and gave the product 2-amino-4-phenyl-6-(phenylsulfanyl)- 3,5-dicyanopyridines in high yields without byproduct. This method has some distinct advantages such as mild reaction conditions, high yields and selectivity, environmental friendliness. Moreover, the ionic liquid could be recovered conveniently and reused.

Cite this article

TIAN Jin-Jin , GUO Hong-Yun . One-Pot Synthesis of 2-Amino-4-phenyl-6-(phenylsulfanyl)-3,5-dicyanopyridines in Ionic Liquids[J]. Chinese Journal of Organic Chemistry, 2012 , 32(01) : 193 -196 . DOI: 10.6023/cjoc1105133

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