Reviews

Progresses in Synthetic Methods of Carbazole and Its Derivatives

  • Fang Xubin ,
  • Fang Lei ,
  • Gou Shaohua
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  • a Pharmaceutical Research Center, Southeast University, Nanjing 211189;
    b Jiangsu Province Hi-Tech Laboratory for Bio-medical Research, Southeast University, Nanjing 211189

Received date: 2011-09-03

  Revised date: 2012-01-10

  Online published: 2012-02-08

Supported by

Project supported by the National Natural Science Foundation of China (No. 81001361) and the Ph.D. Programs Foundation of Ministry of Education of China (No. 20100092120046).

Abstract

Carbazole and its derivatives are a class of important nitrogen-containing heterocyclic compounds possessing various unique properties and biological activity. Herein the current progress of their synthetic strategies reported in the past 5 years is reviewed. The representative examples, which have been divided into four categories according to the usage of different key intermediates, are selected and discussed in detail. Special emphasis is put on the newly developed cyclization reactions which may be useful for the construction of the tricyclic backbone of carbazoles.

Cite this article

Fang Xubin , Fang Lei , Gou Shaohua . Progresses in Synthetic Methods of Carbazole and Its Derivatives[J]. Chinese Journal of Organic Chemistry, 2012 , 32(07) : 1217 -1231 . DOI: 10.6023/cjoc1109031

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