Progresses in Synthetic Methods of Carbazole and Its Derivatives

doi:10.6023/cjoc1109031

Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (07): 1217-1231.DOI: 10.6023/cjoc1109031 Previous Articles Next Articles

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咔唑及其衍生物合成方法研究进展

房旭彬^a,b, 房雷^a,b, 苟少华^a,b

a 东南大学药物研究中心南京 211189;
b 江苏省生物药物高技术研究重点实验室南京 211189

收稿日期:2011-09-03 修回日期:2012-01-10 发布日期:2012-02-08
通讯作者: 苟少华 E-mail:sgou@seu.edu.cn;lei.fang@seu.edu.cn
基金资助:
国家自然科学基金(No. 81001361)和教育部博士点基金青年教师(Nos. 20100092120046)资助项目.

Progresses in Synthetic Methods of Carbazole and Its Derivatives

Fang Xubin^a,b, Fang Lei^a,b, Gou Shaohua^a,b

a Pharmaceutical Research Center, Southeast University, Nanjing 211189;
b Jiangsu Province Hi-Tech Laboratory for Bio-medical Research, Southeast University, Nanjing 211189

Received:2011-09-03 Revised:2012-01-10 Published:2012-02-08
Supported by:
Project supported by the National Natural Science Foundation of China (No. 81001361) and the Ph.D. Programs Foundation of Ministry of Education of China (No. 20100092120046).

Carbazole and its derivatives are a class of important nitrogen-containing heterocyclic compounds possessing various unique properties and biological activity. Herein the current progress of their synthetic strategies reported in the past 5 years is reviewed. The representative examples, which have been divided into four categories according to the usage of different key intermediates, are selected and discussed in detail. Special emphasis is put on the newly developed cyclization reactions which may be useful for the construction of the tricyclic backbone of carbazoles.

Key words: carbazole, derivatives, synthetic methods, progress

Cite this article

Fang Xubin, Fang Lei, Gou Shaohua. Progresses in Synthetic Methods of Carbazole and Its Derivatives[J]. Chin. J. Org. Chem., 2012, 32(07): 1217-1231.

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咔唑及其衍生物合成方法研究进展

Progresses in Synthetic Methods of Carbazole and Its Derivatives

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