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Chinese Journal of Organic Chemistry >

2013 , Vol. 33 >Issue 05: 905 - 914

DOI: https://doi.org/10.6023/cjoc2012010050

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New Progress on Lipases Catalyzed C—C Bond Formation Reactions

  • Ding Yan ,
  • Huang He ,
  • Hu Yi
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  • a College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009;
    b State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing 210009

Received date: 2012-10-28

  Revised date: 2012-12-13

  Online published: 2013-01-04

Supported by

Project supported by the National Natural Science Foundation of China (No. 20936002), the National Natural Science Foundation of China for Yong Scholars (No. 20906049) and the National High Technology Research and Development Program (863 Program, No. 2011AA02A209).

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Abstract

Lipases are the most widely used class of enzymes in organic synthesis due to their high selectivity, mild reaction conditions, environmental acceptability, etc. This article reviews the new progress on lipases catalyzed C—C bond formation reactions, such as aldol condensation, Knoevenagel condensation, Michael addition, Henry reaction, etc.

Key words： lipase; aldol condensation; Knoevenagel condensation; C—C bond formation

Cite this article

Ding Yan , Huang He , Hu Yi . New Progress on Lipases Catalyzed C—C Bond Formation Reactions[J]. Chinese Journal of Organic Chemistry, 2013 , 33(05) : 905 -914 . DOI: 10.6023/cjoc2012010050

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