New Progress on Lipases Catalyzed C—C Bond Formation Reactions

doi:10.6023/cjoc2012010050

Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (05): 905-914.DOI: 10.6023/cjoc2012010050 Previous Articles Next Articles

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脂肪酶催化C—C键形成反应研究新进展

丁雁^a, 黄和^a,b, 胡燚^a,b

a 南京工业大学生物与制药工程学院南京 210009;
b 材料化学工程国家重点实验室南京 210009

收稿日期:2012-10-28 修回日期:2012-12-13 发布日期:2013-01-04
通讯作者: 胡燚,huyi@njut.edu.cn;025-58139942 E-mail:huyi@njut.edu.cn;025-58139942
基金资助:
国家自然科学重点基金(No. 20936002)、国家自然科学青年基金(No. 20906049)和国家高技术研究发展计划(863计划, No. 2011AA02A209)资助项目.

New Progress on Lipases Catalyzed C—C Bond Formation Reactions

Ding Yan^a, Huang He^a,b, Hu Yi^a,b

a College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009;
b State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing 210009

Received:2012-10-28 Revised:2012-12-13 Published:2013-01-04
Supported by:
Project supported by the National Natural Science Foundation of China (No. 20936002), the National Natural Science Foundation of China for Yong Scholars (No. 20906049) and the National High Technology Research and Development Program (863 Program, No. 2011AA02A209).

Lipases are the most widely used class of enzymes in organic synthesis due to their high selectivity, mild reaction conditions, environmental acceptability, etc. This article reviews the new progress on lipases catalyzed C—C bond formation reactions, such as aldol condensation, Knoevenagel condensation, Michael addition, Henry reaction, etc.

Key words: lipase, aldol condensation, Knoevenagel condensation, C—C bond formation

Cite this article

Ding Yan, Huang He, Hu Yi. New Progress on Lipases Catalyzed C—C Bond Formation Reactions[J]. Chin. J. Org. Chem., 2013, 33(05): 905-914.

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脂肪酶催化C—C键形成反应研究新进展

New Progress on Lipases Catalyzed C—C Bond Formation Reactions

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