Chinese Journal of Organic Chemistry >
Vilsmeier Reactions of β-Oxo Amide Derivatives：Applications in the Synthesis of Heterocyclic Compounds
Received date: 2014-03-04
Revised date: 2014-03-15
Online published: 2014-03-26
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 20872136, 21172211).
Our recent research progress based on Vilsmeier reaction of β-oxo amide derivatives is summarized in this account. Series of functionalized β-oxo amide derivatives were designed and prepared, their reaction under the Vilsmeier reaction conditions and the mechanisms involved in these reactions were investigated. Efficient synthetic approaches for four-, five-, and six-membered heterocycles via Vilsmeier reaction of β-oxo amide derivatives had been developed.
Key words： β-oxo amides; Vilsmeier reaction; heterocycles; synthetic method
Liang Yongjiu , Huang Peng , Zhang Rui , Dong Dewen . Vilsmeier Reactions of β-Oxo Amide Derivatives：Applications in the Synthesis of Heterocyclic Compounds[J]. Chinese Journal of Organic Chemistry, 2014 , 34(6) : 1037 -1047 . DOI: 10.6023/cjoc201403006
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