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Chinese Journal of Organic Chemistry >

2016 , Vol. 36 >Issue 11: 2677 - 2682

DOI: https://doi.org/10.6023/cjoc201603036

Articles

Ce(SO4)2·4H2O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones

  • Liu Ruihuan ,
  • Wang Xuli ,
  • Cheng Fei ,
  • Li Fushuang ,
  • Xu Kangping ,
  • Tan Guishan
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  • a Department of Pharmacy, Central South University, Changsha 410013;
    b Xiangya Hospital, Central South University, Changsha 410013

Received date: 2016-03-22

  Revised date: 2016-06-20

  Online published: 2016-07-08

Supported by

Project supported by the National Natural Science Foundation of China (No.31370370),the Science and Technology Planning Project of Hunan Pprovince (No.2013SK5077) and the Social Development of Science and Technology Project of Hainan Province (No.SF201419)

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Abstract

A simple and powerful procedure for the synthesis of flavones and quinolones was developed by using Ce(SO4)2·4H2O as oxidant, readily available 2'-hydroxychalcones and 2'-aminochalcones as raw materials, and dimethyl sulfoxide (DMSO) as solvent at 110℃. The new procedure is characterized with raw material easy to get, low manufacturing cost, mild reaction condi-tions and high yields.

Key words： Ce(SO4)2·; 4H2O; 2'-hydrochalcone; 2'-aminochalcone; flavone; quinolone

Cite this article

Liu Ruihuan , Wang Xuli , Cheng Fei , Li Fushuang , Xu Kangping , Tan Guishan . Ce(SO4)2·4H2O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones[J]. Chinese Journal of Organic Chemistry, 2016 , 36(11) : 2677 -2682 . DOI: 10.6023/cjoc201603036

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