Ce(SO4)2·4H2O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones

doi:10.6023/cjoc201603036

Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (11): 2677-2682.DOI: 10.6023/cjoc201603036 Previous Articles Next Articles

Articles

硫酸铈介导下黄酮和2-芳基-4-喹啉酮衍生物的合成

刘瑞环^a, 王绪礼^a, 成飞^a, 李福双^a, 徐康平^a, 谭桂山^a,b

a 中南大学药学院长沙 410013;
b 中南大学湘雅医院长沙 410013

收稿日期:2016-03-22 修回日期:2016-06-20 发布日期:2016-07-08
通讯作者: 徐康平 E-mail:xukp395@csu.edu.cn
基金资助:
国家自然科学基金（No.31370370）、湖南省科技厅科技计划项目（No.2013SK5077）及海南省社会发展科技专项（No.SF201419）资助项目.

Ce(SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones

Liu Ruihuan^a, Wang Xuli^a, Cheng Fei^a, Li Fushuang^a, Xu Kangping^a, Tan Guishan^a,b

a Department of Pharmacy, Central South University, Changsha 410013;
b Xiangya Hospital, Central South University, Changsha 410013

Received:2016-03-22 Revised:2016-06-20 Published:2016-07-08
Supported by:
Project supported by the National Natural Science Foundation of China (No.31370370),the Science and Technology Planning Project of Hunan Pprovince (No.2013SK5077) and the Social Development of Science and Technology Project of Hainan Province (No.SF201419)

1. Ce(SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones.PDF(2580KB)

Abstract

A simple and powerful procedure for the synthesis of flavones and quinolones was developed by using Ce(SO₄)₂·4H₂O as oxidant, readily available 2'-hydroxychalcones and 2'-aminochalcones as raw materials, and dimethyl sulfoxide (DMSO) as solvent at 110℃. The new procedure is characterized with raw material easy to get, low manufacturing cost, mild reaction condi-tions and high yields.

Key words: Ce(SO₄)₂·, 4H₂O, 2'-hydrochalcone, 2'-aminochalcone, flavone, quinolone

Cite this article

Liu Ruihuan, Wang Xuli, Cheng Fei, Li Fushuang, Xu Kangping, Tan Guishan. Ce(SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones[J]. Chin. J. Org. Chem., 2016, 36(11): 2677-2682.

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硫酸铈介导下黄酮和2-芳基-4-喹啉酮衍生物的合成

Ce(SO₄)₂·4H₂O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones

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