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Chinese Journal of Organic Chemistry >

2018 , Vol. 38 >Issue 4: 955 - 962

DOI: https://doi.org/10.6023/cjoc201708056

Notes

Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application

  • Li Lingdong ,
  • Chi Xiaofang ,
  • Yan Jiawei ,
  • Zhao Zihan
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  • School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin 124221

Received date: 2017-08-27

  Revised date: 2017-11-28

  Online published: 2017-12-08

Supported by

Project supported by the Fundamental Research Funds for the Central Universities (Nos. DUT14RC(3)081, DUT17LK17) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.

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Abstract

In this work, two novel pyridinium N-chloramine precursors were designed and synthesized, both of which contain perfluorophenyl azide (PFPA) unit as the photo-coupling handle. The synthetic precursors were photo immobilized on commercial PU films upon UV (254 nm) light irradiation. After exposure to diluted household bleach, the resulting PU films were rendered biocidal. Antibacterial tests showed that satisfactory was achieved for both surface modified films and that the film grafted with shorter alkyl linker-contained precursor demonstrated even higher biocidal efficacy. Non-leaching antibacterial PU materials were herein developed based on PFPA-coupling strategy, providing a simple and universal method to confer N-chloramines on inert polymer surface for antibacterial application.

Key words： pyridinium N-chloramine precursors; multi-step synthesis; fluorophenyl azide (PFPA) chemistry; biocidal polyurethane film; antimicrobial activity

Cite this article

Li Lingdong , Chi Xiaofang , Yan Jiawei , Zhao Zihan . Synthesis and Immobilization of Pyridinium N-Chloramine Precursors on PU Film for Antibacterial Application[J]. Chinese Journal of Organic Chemistry, 2018 , 38(4) : 955 -962 . DOI: 10.6023/cjoc201708056

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