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Chinese Journal of Organic Chemistry >

2018 , Vol. 38 >Issue 7: 1817 - 1822

DOI: https://doi.org/10.6023/cjoc201801030

Notes

Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O2

  • Qiu Huihua ,
  • Cheng Borui ,
  • Huang Yingsi ,
  • Chen Cui ,
  • Zhou Peng
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  • School of Chemical Engineering, Guangdong University of Petrochemical Technology, Maoming 525000

Received date: 2018-01-23

  Revised date: 2018-03-26

  Online published: 2018-04-12

Supported by

Project supported by the National Natural Science Foundation of China (No. 21602035) and the Natural Science Foundation of Guangdong Province (No. 2016A030307030).

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Abstract

An economic and environmental synthestic method for 3-chloroindenes from o-(alkynyl)styrenes through tandem reactions including choropalladation/Heck cross coupling in Pd/O2 system was reported. Taking green dioxygen as sole oxidant and LiCl as chlorine source, 13 functionalized 3-chloroindenes could be synthesized in moderate to high yield without the addition of CuCl2

Key words： Pd-catalyzed; dioxygen; chloropalladation; indene

Cite this article

Qiu Huihua , Cheng Borui , Huang Yingsi , Chen Cui , Zhou Peng . Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O2[J]. Chinese Journal of Organic Chemistry, 2018 , 38(7) : 1817 -1822 . DOI: 10.6023/cjoc201801030

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