Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O2

doi:10.6023/cjoc201801030

Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (7): 1817-1822.DOI: 10.6023/cjoc201801030 Previous Articles Next Articles

Notes

Pd/O₂体系中邻炔基苯乙烯类衍生物的氯钯化/Heck串联反应研究

邱会华, 成博睿, 黄颖思, 陈翠, 周鹏

广东石油化工学院化学工程学院茂名 525000

收稿日期:2018-01-23 修回日期:2018-03-26 发布日期:2018-04-12
通讯作者: 邱会华 E-mail:qh198511@163.com
基金资助:
国家自然科学基金（No.21602035）和广东省自然科学基金（No.2016A030307030）资助项目.

Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O₂

Qiu Huihua, Cheng Borui, Huang Yingsi, Chen Cui, Zhou Peng

School of Chemical Engineering, Guangdong University of Petrochemical Technology, Maoming 525000

Received:2018-01-23 Revised:2018-03-26 Published:2018-04-12
Contact: 10.6023/cjoc201801030 E-mail:qh198511@163.com
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21602035) and the Natural Science Foundation of Guangdong Province (No. 2016A030307030).

1. Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O₂.PDF(2053KB)

Abstract

An economic and environmental synthestic method for 3-chloroindenes from o-(alkynyl)styrenes through tandem reactions including choropalladation/Heck cross coupling in Pd/O₂ system was reported. Taking green dioxygen as sole oxidant and LiCl as chlorine source, 13 functionalized 3-chloroindenes could be synthesized in moderate to high yield without the addition of CuCl₂

Key words: Pd-catalyzed, dioxygen, chloropalladation, indene

Cite this article

Qiu Huihua, Cheng Borui, Huang Yingsi, Chen Cui, Zhou Peng. Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O₂[J]. Chin. J. Org. Chem., 2018, 38(7): 1817-1822.

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Pd/O₂体系中邻炔基苯乙烯类衍生物的氯钯化/Heck串联反应研究

Research on the Tandem Reaction via Chloropalladation/Heck Cross Coupling of o-(Alkynyl)styrenes with Pd/O₂

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Pd/O2体系中邻炔基苯乙烯类衍生物的氯钯化/Heck串联反应研究