Notes

Synthesis and Insecticidal Activity of Terpinen-4-ol Derivatives Containing Oxime Ether

  • Lei Peng ,
  • Ding Xinji ,
  • Wu Yuanyong ,
  • Ma Zhiqing
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  • College of Plant Protection, Northwest A & F University, Yangling 712100

Received date: 2018-12-21

  Revised date: 2019-01-21

  Online published: 2019-03-29

Supported by

Project supported by the National Natural Science Foundation of China (No. 31572029) and the Starting Research Fund from the Northwest A&F University (No. 00200-Z109021809).

Abstract

In order to discover high activity lead compound, based on our previous studies, a series of terpinen-4-ol deri- vatives containing oxime ether were designed and synthesized. The bioassay results showed that the target compounds displayed good insecticidal activity against Mythimna separata (Walker). Especially, compound 3a exhibited satisfied activity with the LD50 value of 0.0054 mg/insect, which is 19.1 times than terpinen-4-ol. As a high activity compound with simple structure, 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one O-prop-2-yn-1-yl oxime (3a) could be a lead compound for further study.

Cite this article

Lei Peng , Ding Xinji , Wu Yuanyong , Ma Zhiqing . Synthesis and Insecticidal Activity of Terpinen-4-ol Derivatives Containing Oxime Ether[J]. Chinese Journal of Organic Chemistry, 2019 , 39(7) : 2070 -2074 . DOI: 10.6023/cjoc201812039

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