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Chinese Journal of Organic Chemistry >

2020 , Vol. 40 >Issue 7: 2153 - 2158

DOI: https://doi.org/10.6023/cjoc202002014

γ-Aluminum Oxide-Mediated Iodination of Terminal Alkynes

  • Yao Ming ,
  • Zhang Jingjing ,
  • Yang Sen ,
  • Xiong Hangxing
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  • a College of Chemical Engineering and Pharmacy, Jingchu University of Technology, Jingmen, Hubei 448000;
    b School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430205

Received date: 2020-02-13

  Revised date: 2020-03-27

  Online published: 2020-04-13

Supported by

Project supported by the Science Technology Foundation for Creative Research Group of Hubei Department of Education (No. T201719).

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Abstract

A simple two-step, one-pot synthesis of 1,2,2-triiodovinyl derivatives from terminal alkynes using N-iodosuc-cinimide and iodine as precursors, activated with γ-aluminum oxide is developed. This approach resulted in moderate to excellent yields, good functional group tolerance and utilization of an inexpensive catalyst.

Key words： terminal alkyne; iodination; aluminum oxide; 1,2,2-triiodovinyl derivative; one-pot process

Cite this article

Yao Ming , Zhang Jingjing , Yang Sen , Xiong Hangxing . γ-Aluminum Oxide-Mediated Iodination of Terminal Alkynes[J]. Chinese Journal of Organic Chemistry, 2020 , 40(7) : 2153 -2158 . DOI: 10.6023/cjoc202002014

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