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Chinese Journal of Organic Chemistry >

2020 , Vol. 40 >Issue 10: 3289 - 3299

DOI: https://doi.org/10.6023/cjoc202003014

Synthetic Progress of Natural Products Gracilioethers and Hippolachnin A

  • Wu Jinghua ,
  • Wang Cheng ,
  • Chen Pengquan ,
  • Ma Zhiqiang
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  • Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry & Chemical Engineering, South China University of Technology, Guangzhou 510641

Received date: 2020-03-06

  Revised date: 2020-04-08

  Online published: 2020-04-17

Supported by

Project supported by the National Program on Key Research Project (No. 2016YFA0602900), the Science and Technology Program of Guangzhou City (No. 201707010073) and the National Natural Science Foundation of China (Nos. 21672073, 21871098).

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Abstract

Gracilioethers and hippolachnin A were isolated from marine sponge. Gracilioethers showed antimalarial activity while hippolachnin A exhibited strong antifungal activity. Their fascinating structures and outstanding biological activities have attracted attentions from chemists. Progress on the synthesis of gracilioethers with tricyclic skeleton and hippolachnin A are reviewed in terms of the key strategies employed.

Key words： gracilioether; hippolachnin A; natural product; total synthesis

Cite this article

Wu Jinghua , Wang Cheng , Chen Pengquan , Ma Zhiqiang . Synthetic Progress of Natural Products Gracilioethers and Hippolachnin A[J]. Chinese Journal of Organic Chemistry, 2020 , 40(10) : 3289 -3299 . DOI: 10.6023/cjoc202003014

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