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Chinese Journal of Organic Chemistry >

2020 , Vol. 40 >Issue 4: 1043 - 1049

DOI: https://doi.org/10.6023/cjoc201910024

An Intramolecular Charge Transfer (ICT)-Based Fluorescent Probe of Hydrogen Sulphide under pH Control Strategy

  • Zhu Jihua ,
  • Zhang Hao ,
  • Liu Min ,
  • Liu Jingjiang ,
  • Liao Yuan ,
  • Quan Zhengjun ,
  • Wang Xicun
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  • a College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070;
    b College of Chemistry and Chemical Engineering, Longdong University, Qingyang, Gansu 745000

Received date: 2019-10-20

  Revised date: 2019-11-12

  Online published: 2020-05-06

Supported by

Project supported by the Longyuan Youth Innovative and Entrepreneurial Talents Project (No. 2019-39) and the Research Project of Higher Education in Gansu Province (No. 2018A-004).

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Abstract

Hydrogen sulfide (H2S) and pH play a most important role in vivo and environment. A fluorescent probe for fast and sensitive detection of H2S and pH are of vital importance for research their functions. A naphthalimide-based fluorescent probe L has been designed and synthesized based on intramolecular charge transfer (ICT) mechanism by utilizing azide as recognition site. The probe L has demonstrated good stability in the pH range of 4~11. It showed satisfactory sensitivity and rapidly response (less than 3 min) to H2S. An excellent linear relationship (R2=0.99823) displayed in the range of H2S concentrations from 0 μmol·L-1 to 20 μmol·L-1 and the detection limit was 1.18 μmol·L-1. Furthermore, in the present 30 equiv. H2S, it was successfully applied to detection of pH with good linear relationship (R2=0.98764) in the pH range of 2~6.5. This methods provide a reference for detection of H2S and pH value in the presence of 30 equiv. H2S, which have potential application prospects in analytical detection and pathological analysis.

Key words： hydrogen sulfide; pH; fluorescent probe; theoretical calculations; ICT mechanism

Cite this article

Zhu Jihua , Zhang Hao , Liu Min , Liu Jingjiang , Liao Yuan , Quan Zhengjun , Wang Xicun . An Intramolecular Charge Transfer (ICT)-Based Fluorescent Probe of Hydrogen Sulphide under pH Control Strategy[J]. Chinese Journal of Organic Chemistry, 2020 , 40(4) : 1043 -1049 . DOI: 10.6023/cjoc201910024

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