Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (4): 1043-1049.DOI: 10.6023/cjoc201910024 Previous Articles     Next Articles


朱继华a,b, 张浩a, 刘敏a, 刘旌江a, 廖原a, 权正军a, 王喜存a   

  1. a 西北师范大学化学化工学院 兰州 730070;
    b 陇东学院化学化学工院 甘肃庆阳 745000
  • 收稿日期:2019-10-20 修回日期:2019-11-12 发布日期:2020-05-06
  • 通讯作者: 权正军, 王喜存;
  • 基金资助:

An Intramolecular Charge Transfer (ICT)-Based Fluorescent Probe of Hydrogen Sulphide under pH Control Strategy

Zhu Jihuaa,b, Zhang Haoa, Liu Mina, Liu Jingjianga, Liao Yuana, Quan Zhengjuna, Wang Xicuna   

  1. a College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070;
    b College of Chemistry and Chemical Engineering, Longdong University, Qingyang, Gansu 745000
  • Received:2019-10-20 Revised:2019-11-12 Published:2020-05-06
  • Supported by:
    Project supported by the Longyuan Youth Innovative and Entrepreneurial Talents Project (No. 2019-39) and the Research Project of Higher Education in Gansu Province (No. 2018A-004).

Hydrogen sulfide (H2S) and pH play a most important role in vivo and environment. A fluorescent probe for fast and sensitive detection of H2S and pH are of vital importance for research their functions. A naphthalimide-based fluorescent probe L has been designed and synthesized based on intramolecular charge transfer (ICT) mechanism by utilizing azide as recognition site. The probe L has demonstrated good stability in the pH range of 4~11. It showed satisfactory sensitivity and rapidly response (less than 3 min) to H2S. An excellent linear relationship (R2=0.99823) displayed in the range of H2S concentrations from 0 μmol·L-1 to 20 μmol·L-1 and the detection limit was 1.18 μmol·L-1. Furthermore, in the present 30 equiv. H2S, it was successfully applied to detection of pH with good linear relationship (R2=0.98764) in the pH range of 2~6.5. This methods provide a reference for detection of H2S and pH value in the presence of 30 equiv. H2S, which have potential application prospects in analytical detection and pathological analysis.

Key words: hydrogen sulfide, pH, fluorescent probe, theoretical calculations, ICT mechanism