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Chinese Journal of Organic Chemistry >

2022 , Vol. 42 >Issue 1: 172 - 180

DOI: https://doi.org/10.6023/cjoc202107038

ARTICLES

Rh(III)-Catalyzed Annulation of Azobenzenes with Vinylene Carbonate

  • Wenjie Zhang ,
  • Chao Li ,
  • Bochao Wang ,
  • Hui Gao ,
  • Hongji Li
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  • a Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, School of Chemistry and Materials Science, Huaibei Normal University, Huaibei, Anhui 235000
    b State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, Guangxi 541004
* Corresponding authors. E-mail: ;

Received date: 2021-07-18

  Revised date: 2021-09-16

  Online published: 2021-09-27

Supported by

National Natural Science Foundation of China(21772061); Research Funding for Outstanding Young Talents in Colleges and Universities of Anhui Province(gxyq2020015); State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University)(CMEMR2021-B14)

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Abstract

A mild Rh(III)-catalyzed annulation of azobenzenes with vinylene carbonate via inert C—H bond activation has been developed. In this reaction system, vinylene carbonate provides one vinyl carbon for the construction of indazole backbone, and leaves the other one for the formation of aldehyde. This annulation enables the direct synthesis of 2H-indazole- 3-carbaldehyde with excellent regioselectivity in moderate to good yields.

Key words： Rh catalysis; azobenzene; vinylene carbonate; annulation

Cite this article

Wenjie Zhang , Chao Li , Bochao Wang , Hui Gao , Hongji Li . Rh(III)-Catalyzed Annulation of Azobenzenes with Vinylene Carbonate[J]. Chinese Journal of Organic Chemistry, 2022 , 42(1) : 172 -180 . DOI: 10.6023/cjoc202107038

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