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Chinese Journal of Organic Chemistry >

2022 , Vol. 42 >Issue 6: 1820 - 1830

DOI: https://doi.org/10.6023/cjoc202201011

ARTICLES

Visible Light Induced Arylfluoroalkylation of Activated Alkenes

  • Xinling Li ,
  • Weidong Meng ,
  • Xiuhua Xu ,
  • Yan'gen Huang
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  • a Key Laboratory of Science and Technology of Eco-Textiles, Ministry of Education, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620
    b Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
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Received date: 2022-01-10

  Revised date: 2022-01-29

  Online published: 2022-02-18

Supported by

National Natural Science Foundation of China(2199121)

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Abstract

Fluorine-containing compounds have a wide range of applications in the fields of biomedicine and materials, and the development of synthetic methodology for fluorine-containing compounds is very important. Using fac-Ir(ppy)3 as catalyst, a wide variety of amides containing fluoroalkyl substituted α-quaternary carbon center were prepared with N-aryl-N-(aryl- sulfonyl)-2-methyl acrylamides as starting materials by visible light induced cascade fluoroalkyl radical addition, aryl migration and desulfonylation. The reaction conditions are mild, and possess good functional group compatibility.

Key words： photocatalysis; fluoroalkylation; aryl migration; desulfonylation; α-quaternary carbon center; amide

Cite this article

Xinling Li , Weidong Meng , Xiuhua Xu , Yan'gen Huang . Visible Light Induced Arylfluoroalkylation of Activated Alkenes[J]. Chinese Journal of Organic Chemistry, 2022 , 42(6) : 1820 -1830 . DOI: 10.6023/cjoc202201011

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