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Chinese Journal of Organic Chemistry >

2022 , Vol. 42 >Issue 7: 2134 - 2139

DOI: https://doi.org/10.6023/cjoc202202014

ARTICLES

β-H Regioselective Trifluoromethyl Sulfonylation of Aryl Ethylene

  • Linlin Xu ,
  • Meijun Lan ,
  • Muyu Zhang ,
  • Yongqi Zhang ,
  • Yuhao Feng ,
  • Liangce Rong ,
  • Jinpeng Zhang
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  • aSchool of Public Health, Key Laboratory of Human Genetics and Environmental Medicine, Xuzhou Medical University, Xuzhou 221004
    bSchool of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116
* E-mail: ;

Received date: 2022-02-11

  Revised date: 2022-04-06

  Online published: 2022-04-15

Supported by

Natural Science Foundation of the Jiangsu Higher Education Institutions of China(18KJA150004); Undergraduate Innovation and Entrepreneurship Training Program and the Brand Major of Universities in Jiangsu Province

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Abstract

In the presence of cerium ammonium nitrate, the β-H radical sulfonation reaction of aryl ethylene with sodium trifluoromethanesulfinate was reported to give highly regioselective trans-alkene. The advantages of this method were cheap and easy to obtain reaction reagents, mild reaction conditions and simple operation. Moreover, the reaction had a high regioselective and configurational selectivity.

Key words： aryl ethylene; trifluoromethyl sulfonylation; regioselective reaction; radical

Cite this article

Linlin Xu , Meijun Lan , Muyu Zhang , Yongqi Zhang , Yuhao Feng , Liangce Rong , Jinpeng Zhang . β-H Regioselective Trifluoromethyl Sulfonylation of Aryl Ethylene[J]. Chinese Journal of Organic Chemistry, 2022 , 42(7) : 2134 -2139 . DOI: 10.6023/cjoc202202014

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