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Chinese Journal of Organic Chemistry >

2022 , Vol. 42 >Issue 7: 2070 - 2078

DOI: https://doi.org/10.6023/cjoc202203002

ARTICLES

Reaction of Tandem Addition of Aliphatic Amines to Alkenylnitriles Catalyzed by Tris(o-dimethylaminobenzyl)yttrium

  • Jinsong Hou ,
  • Gaosheng Yang
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  • aMOE Key Laboratory of Functional Molecular Solids, Anhui Laboratory of Molecule-Based Materials, Institute of Organic Chemistry, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241002
    bCollege of Material and Chemical Engineering, Chuzhou University, Chuzhou, Anhui 239000
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Received date: 2022-03-01

  Revised date: 2022-04-05

  Online published: 2022-04-29

Supported by

National Natural Science Foundation of China(21672005); National Natural Science Foundation of China(20972001)

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Abstract

Amidines are nitrogen-containing compounds with very important physiological activities. There are few reports on the synthesis of cyclic amidines catalyzed by rare earth complexes. In this paper, a series of cyclic amidines were synthesized by the tandem reaction of N—H to CN and “C=C” with simple trialkyl rare earth metal complex Y(CH2C6H4NMe2-o)3 as precatalyst with 22%~96% yields. The method has the characteristics of simple catalyst, mild reaction conditions and 100% atomic utilization. It provides a new way for the construction of cyclic amidines.

Key words： rare earth metal complexes; tandem reaction; aliphatic amine; amidine; synthesis

Cite this article

Jinsong Hou , Gaosheng Yang . Reaction of Tandem Addition of Aliphatic Amines to Alkenylnitriles Catalyzed by Tris(o-dimethylaminobenzyl)yttrium[J]. Chinese Journal of Organic Chemistry, 2022 , 42(7) : 2070 -2078 . DOI: 10.6023/cjoc202203002

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