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Chinese Journal of Organic Chemistry >

2023 , Vol. 43 >Issue 2: 436 - 454

DOI: https://doi.org/10.6023/cjoc202208020

Research Progress on the Synthesis of Nitrogen-Containing Compounds with Cyanamide as a Building Block

  • Jianglong Wu ,
  • Zhongjie Wang ,
  • Chenyu Wang ,
  • Yan Wang ,
  • Hongjun Li ,
  • Hui Luo ,
  • Hao Li ,
  • Fuqiang Wang ,
  • Dianjun Li ,
  • Jinhui Yang
Expand
  • College of Chemistry and Chemical Engineering/State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, Ningxia University, Yinchuan 750021
†(These authors contributed equally to this work).
* Corresponding authors. E-mail: ;
;

Received date: 2022-08-16

  Revised date: 2022-09-18

  Online published: 2022-11-01

Supported by

Ministry-Level Natural Science Other Projects(2019NXZD1); Scientific and Technological Research (Support) Project of Ningxia(2021BEG02001); Scientific and Technological Research (Support) Project of Ningxia(2021BEE03003); Key Research and Development Project of Ningxia(2022BDE03009)

Fold

Abstract

Nitrogen-containing compounds are widely found in many natural products and have a wide range of pharmaco- logical and physiological activities. Furthermore, they have comprehensive applications in medicine and pesticide fields, industry and multi-functional materials. Great advances in the synthesis of these compounds have been sprung up, a diversity of synthetic methods of them via cyanamide (NH2-CN) as raw material were exploited in recent years. The research progress on the synthesis of nitrogen-containing compounds through cyanamide as a building block is introduced comprehensively. Moreover, their characteristics, rules, advantages and disadvantages are summarized and discussed for the development of new synthetic methodologies and reactions of nitrogen-containing compounds.

Key words： cyanamide; natural origin; nitrogen-containing compound; pharmaceutical

Cite this article

Jianglong Wu , Zhongjie Wang , Chenyu Wang , Yan Wang , Hongjun Li , Hui Luo , Hao Li , Fuqiang Wang , Dianjun Li , Jinhui Yang . Research Progress on the Synthesis of Nitrogen-Containing Compounds with Cyanamide as a Building Block[J]. Chinese Journal of Organic Chemistry, 2023 , 43(2) : 436 -454 . DOI: 10.6023/cjoc202208020

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