Chinese Journal of Organic Chemistry >
Recent Progress on the Synthesis of Benzazepine Derivatives via Radical Cascade Cyclization Reactions
Received date: 2022-09-19
Revised date: 2022-10-17
Online published: 2022-11-08
Supported by
National Natural Science Foundation of China(22171177); National Natural Science Foundation of China(51973107)
Benzazepines are a kind of important seven-membered nitrogen-containing heterocyclic compounds, which are extensively exisited in natural products and pharmaceuticals, and have versatile biological activity. Therefore, great attention has been focused on the green and efficient synthesis of the benzazepines. In recent years, radical cascade cyclization reactions have gradually been developed as a powerful tool for the construction of benzazepines owing to their unique advantages. In this minireview, according to the different driving force of reaction, the research progress on the synthesis of benzazepines by radical cascade cyclization reactions in the past five years is systematically summarized in terms of photochemical reactions, electrochemical reactions and thermochemical reactions.
Qian Xiao , Qing-Xiao Tong , Jian-Ji Zhong . Recent Progress on the Synthesis of Benzazepine Derivatives via Radical Cascade Cyclization Reactions[J]. Chinese Journal of Organic Chemistry, 2022 , 42(12) : 3979 -3994 . DOI: 10.6023/cjoc202209025
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