钛基多孔HA/SiO2 复合涂层的制备及性能研究

doi:10.6023/A1107063

化学学报 ›› 2012, Vol. 70 ›› Issue (03): 235-240.DOI: 10.6023/A1107063 上一篇下一篇

研究论文

钛基多孔HA/SiO₂ 复合涂层的制备及性能研究

黄紫洋, 张岚, 梁广超

福建师范大学化学与材料学院福州 350007

投稿日期:2011-07-06 修回日期:2011-08-22 发布日期:2011-09-26
通讯作者: 黄紫洋 E-mail:zyhuang@fjnu.edu.cn
基金资助:
国家自然科学基金(No. 30970887)资助项目.

Study on Fabrication and Properties of Porous HA/SiO₂ Composite Coating on Titanium Substrate

Huang Ziyang, Zhang Lan, Liang Guangchao

College of Chemistry and Materials Science, Fujian Normal University, Fuzhou 350007

Received:2011-07-06 Revised:2011-08-22 Published:2011-09-26
Supported by:
Project supported by the National Natural Science Foundation of China (No. 30970887).

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摘要/Abstract

为了制得表面多孔且与基材结合强度高的羟基磷灰石(HA)涂层, 实验中以正丁醇为分散介质, 以SiO₂ 粉末为添加剂, 纯钛片为基材, 电泳沉积制备羟基磷灰石/二氧化硅/壳聚糖/(HA/SiO₂/CS)复合涂层, 经后续热处理得到多孔HA/SiO₂ 复合涂层, 采用扫描电镜(SEM)、傅立叶红外光谱仪(FT-IR)、X 射线衍射仪(XRD)、万能材料试验机对涂层的表面形貌、组成、结构和结合强度进行测试和表征, 并通过模拟体液(SBF)浸泡法对复合涂层的生物活性进行评价. 结果表明: 当悬浮液中的HA/SiO₂/CS 质量比为1:1:1 时, 制得的HA/SiO₂/CS 涂层经700 ℃热处理后获得的HA/SiO₂复合涂层孔洞分布均匀, 大孔孔径在10～15 μm, 小孔孔径在1～5 μm; 涂层与基材的结合强度达到25.5 MPa; 多孔HA/SiO₂ 复合涂层在SBF 中浸泡7 d 后, 涂层表面碳磷灰石化; 说明实验中添加SiO₂ 所制得的多孔HA/SiO₂ 复合涂层与钛基材结合强度高, 且具有良好的生物活性.

关键词: 羟基磷灰石, 电泳沉积, HA/SiO₂ 复合涂层, 多孔性, 生物活性

In order to obtain porous hydroxyapatite (HA) coating with high bonding strength to substrate, hydroxyapatite/silica/chitosan (HA/SiO₂/CS) composite coatings were prepared on titanium substrate by electrophoretic deposition (EPD) in n-butylalcohol as dispersion medium and SiO₂ powder as additive. And then a porous HA/SiO₂ composite coating was obtained by sequentially sintering treatment. The surface morphology, chemical composition, phase composition and the bonding strength between composite coating and substrate were characterized by scanning electron microscopy (SEM), fourier transform infrared spectrometer (FT-IR), X-ray diffraction (XRD) and shear strength testing experiment, respectively. The bioactivity of the porous HA/SiO₂ composite coating was evaluated by immersion in simulated body fluid (SBF). The results showed that the porous HA/SiO₂ composite coating with uniform cavities was obtained by sintering at 700 ℃ from the HA/SiO₂/CS composite coating fabricated by EPD in suspension with 1:1:1 mass ratio of HA/SiO₂/CS. The large-pore diameter was about 10～15 μm, the small-pore diameter was about 1～5 μm, and the bonding strength between composite coating and substrate was up to 25.5 MPa. The coating surface was covered totally by carbonate-apatite after immersion in SBF for 7 d. This porous HA/SiO₂ composite coating exhibits a good bioactivity and high bonding strength between composite coating and substrate.

Key words: hydroxyapatite, electrophoretic deposition, HA/SiO₂ composite coating, porousity, bioactivity

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黄紫洋, 张岚, 梁广超. 钛基多孔HA/SiO₂ 复合涂层的制备及性能研究[J]. 化学学报, 2012, 70(03): 235-240.

Huang Ziyang, Zhang Lan, Liang Guangchao. Study on Fabrication and Properties of Porous HA/SiO₂ Composite Coating on Titanium Substrate[J]. Acta Chimica Sinica, 2012, 70(03): 235-240.

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参考文献

1 Yang, J. Z.; Sultana, R.; Hu, X. Z.; Huang, Z. H. J. Eur. Ceram. Soc. 2011, 31, 2065.

2 Jaworski, R.; Pierlot, C.; Pawlowski, L.; Bigan, M.; Martel, M. Surf. Coat. Technol. 2009, 15, 2092.

3 Sureshbabu, S.; Komath, M.; Shibli, S. M. A.; Varma, H. K. Mater. Res. Innovations 2011, 15, 178.

4 Zhang, X.-K.; Chen, X.-F.; Wang, Y.-J.; Zhang, M.-M. Acta Chim. Sinica 2005, 63, 2077 (in Chinese). (张晓凯, 陈晓峰, 王迎军, 张梅梅, 化学学报, 2005, 63,2077.)

5 Wang, Y.-B.; Lu, X.; Feng, B.; Qu, S.-X.; Weng, J. J. Inorg. Mater. 2011, (1), 61 (in Chinese). (王英波, 鲁雄, 冯波, 屈树新, 翁杰, 无机材料学报,2011, (1), 61.)

6 Huang, Z.-Y.; Liu, R.-F.; Xiao, X.-F. J. Chin. Ceram. Soc. 2003, 31(6), 591 (in Chinese). (黄紫洋, 刘榕芳, 肖秀峰, 硅酸盐学报, 2003, 31(6), 591.)

7 Zhao, J.; Guo, L. Y.; Yang, X. B.; Weng, J. Appl. Surf. Sci. 2008, 255, 2942.

8 Kokubo, T.; Kim, H. M.; Kawashita, M.; Nakamura, T. J. Mater. Sci. Mater. Med. 2004, 15(2), 99.

9 Wang, X.-Y.; Han, Y.-C.; Dai, H.-L.; Li, S.-P. Chin. J. Biomed. Eng. 2003, (3), 274 (in Chinese). (王欣宇, 韩颖超, 戴红莲, 李世普, 中国生物医学工程学报, 2003, (3), 274.)

10 Wang, Z.-C.; Tang, Y.; Huang, L.-M. J. Funct. Mater. 2006, 37(6), 944 (in Chinese). (王周成, 唐毅, 黄龙门, 功能材料, 2006, 37(6), 944.)

11 Huang, Z.-Y.; Li, P.; Liu, R.-F.; Xiao, X.-F. Acta Mater. Compositae Sinica 2010, 27(5), 68 (in Chinese). (黄紫洋, 李鹏, 刘榕芳, 肖秀峰, 复合材料学报, 2010, 27(5), 68.)

12 Pang, X.; Zhitomirsky, I. J. Mater. Character. 2007, 58, 339.

13 Zhu, D.-C.; Xiao, X.-F.; Liu, R.-F.; Fu, H.-P.; Xu, J.; Wang, M.-F. J. Synth. Cryst. 2010, 39(1), 214 (in Chinese). (朱丹琛, 肖秀峰, 刘榕芳, 傅涵萍, 徐佳, 王梅芳, 人工晶体学报, 2010, 39(1), 214.)

14 Liu, R.-F.; Xiao, X.-F.; Xu, D.-X. J. Chin. Ceram. Soc. 2003, 31(6), 615 (in Chinese). (刘榕芳, 肖秀峰, 许道璇, 硅酸盐学报, 2003, 31(6), 615.)

15 Kokubo, T.; Takadama, H. J. Biomater. 2006, 27, 2907.

16 Li, P.; Huang, Z.-Y.; Liu, R.-F.; Xiao, X.-F. J. Chin. Ceram.Soc. 2009, 37(11), 1864 (in Chinese). (李鹏, 黄紫洋, 刘榕芳, 肖秀峰, 硅酸盐学报, 2009, 37(11), 1864.)

17 Rezwan, K.; Chen, Q. Z.; Blaker, J. J.; Boccaccini, A. R. J. Biomater. 2006, 27, 3413.

18 Huang, X.-H.; Yan, X.-X.; Han, L.; Yi, J. Acta Chim. Sinica 2006, 64, 851 (in Chinese).(黄晓晖, 严晓霞, 韩露, 易静, 化学学报, 2006, 64, 851.)

19 Morks, M. F. J. Mech. Behave Biomed. Mater. 2008, 1, 105.

20 Zhao, L.; Yu, J. G.; Fan, J. J.; Zhai, P. C.; Wang, S. M. Electrochem. Commun. 2009, 11, 2052.

21 Laxmidhar, B.; Meilin, L. J. Process Mater. Sci. 2007, 52, 1.

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钛基多孔HA/SiO₂ 复合涂层的制备及性能研究

Study on Fabrication and Properties of Porous HA/SiO₂ Composite Coating on Titanium Substrate

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