化学学报 ›› 1983, Vol. 41 ›› Issue (9): 853-856. 上一篇    下一篇

研究论文

青蒿素及其类似物的结构和合成 VIII:^1H核磁共振测定青蒿素降解物及有关化合物的构型

陈朝环;周维善   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1983-09-15

Studies on structure and synthesis of arteannuin and related compounds VIII: Determination of configuration of arteannuin degradation products and related compounds by ^1H NMR spectroscopy

CHEN CHAOHUAN;ZHOU WEISHAN   

  • Published:1983-09-15

关键词: 测定, 核磁共振谱法, 化学位移, 青蒿素, 构型, 降解产物

The present report deals with the stereochemistry of the degradation products of arteannuin and some intermediates of its total synthesis. The configurations of 13-CH3 and lactone ring are deduced by using spin-spin coupling constants and the pattern of 11-H as well as the NOE results from 1H NMR spectroscopy.

Key words: DETERMINATION, NMR SPECTROMETRY, CHEMICAL SHIFT, ARTEANNUIN, CONFIGURATION, DEGRADATION PRODUCTS

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