Acta Chimica Sinica ›› 2012, Vol. 0 ›› Issue (05): 525-529 .DOI: 10.6023/A1107292     Next Articles

Full Papers


江金强a, 陈欣a, 殷明a, 王周平b, 刘晓亚a, 陈明清a   

  1. a 江南大学化学与材料工程学院 无锡 214122;
    b 江南大学食品学院 无锡 214122
  • 投稿日期:2011-07-29 修回日期:2011-10-12 发布日期:2011-11-28
  • 通讯作者: 江金强
  • 基金资助:

    国家自然科学基金(Nos. 20704017, 50973044)、江苏省高校“青蓝工程”资助项目、中央高校基本科研业务费专项资金(No. JUSRP31003)资助项目.

Design and Synthesis of α-Cyclodextrin Modified Coumarin

Jiang Jinqianga, Chen Xina, Yin Minga, Wang Zhoupingb, Liu Xiaoyaa, Chen Mingqinga   

  1. a School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122;
    b School of Food Science and Technology, Jiangnan University, Wuxi 214122
  • Received:2011-07-29 Revised:2011-10-12 Published:2011-11-28
  • Supported by:

    Project supported by the National Natural Science Foundation of China (NSFC) (under Grant Nos. 20704017, 50973044), the Qing Lan Project of Jiangsu Province and the Fundamental Research Funds for the Central Universities (No. JUSRP31003).

Using epichlorohydrin as the bridged unit, the water-soluble α-cyclodextrin (α-CD) was introduced to modify 7-hydroxy-4-methylcoumarin and prepare the novel α-cyclodextrin modified coumarin (α-CD-C), which was characterized by FTIR, 1H NMR and LCMS. The photo-dimerization experiment showed that α-CD-C could photo-dimerize upon 365 nm irradiation, and then photo-de-crosslink upon the subsequent 254 nm irradiation. And by comparing the photo-dimerization degree upon 365 nm and 254 nm irradiation, it was concluded that the photo-dimerization reaction is only partially reversible.

Key words: coumarin, cyclodextrin, synthesis, UV, photo-dimerization