Acta Chimica Sinica ›› 2012, Vol. 0 ›› Issue (05): 537-543 .DOI: 10.6023/A1109031 Previous Articles     Next Articles

Full Papers

MnO2 纳米溶胶-甲醛化学发光体系及其分析应用研究

杜建修, 王虹   

  1. 陕西省生命分析化学重点实验室 陕西师范大学化学化工学院 西安 710062
  • 收稿日期:2011-09-03 修回日期:2011-10-24 出版日期:2012-03-14 发布日期:2011-11-01
  • 通讯作者: 杜建修 E-mail:jxdu@snnu.edu.cn
  • 基金资助:

    陕西省自然科学基础研究计划项目(No. 2011JM2004), 中央高校基本科研业务费专项资金(No. GK200902012)和陕西师范大学优秀科技预研项目(No.200902016)资助项目.

Chemiluminescence of Nano-Colloidal MnO2 with Formaldehyde and Its Analytical Application

Du Jianxiu, Wang Hong   

  1. Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062
  • Received:2011-09-03 Revised:2011-10-24 Online:2012-03-14 Published:2011-11-01
  • Supported by:

    Project was supported by the Natural Science Foundation of Shaanxi Province (No. 2011JM2004), Fundamental Research Funds for the Central Universities (No. GK200902012), Excellent Preresearch Projects of Science and Technology of Shaanxi Normal University (No. 200902016).

Water-soluble forms of colloidal MnO2 were prepared by the chemical reduction of KMnO4 with Na2S2O3 under neutral aqueous condition. The as-prepared colloidal MnO2 solution is dark-brown, transparent, stable, and possesses the maximum absorption peak at 375 nm and an average diameter of 40 nm. The as-prepared nano-colloidal MnO2 was found to react with formaldehyde to generate weak chemiluminescence (CL) under acidic condition. The effects of more than 30 pharmaceuticals on the nano-colloidal MnO2-formaldehyde CL system were tested. Pharmaceuticals including phenothiazines and aminoethanethiols were observed to enhance the CL signal significantly. The experimental conditions were well optimized and the analytical figures for five phenothiazines and four aminoethanethiols were presented. The method was validated by the analysis of perphenazine in tablets and chlorpromazine hydrochloride in swine feed. The CL reaction mechanism was discussed by the study of CL spectra, fluorescence spectra, UV-vis absorption spectra, and other experiments. All of CL reactions had the same maximum emission wavelength about 640 nm, which suggested that the CL emitter was independent of analytes. The CL signal was inhibited obviously by single-state oxygen scavengers, sodium azide and 1,4-diazabicyclo[2,2,2]octane, indicating that single-state oxygen dimer was the potential CL emitter for the present CL reaction.

Key words: chemiluminescence, nano-colloidal MnO2, formaldehyde, analytical application