Acta Chimica Sinica ›› 2018, Vol. 76 ›› Issue (4): 237-245.DOI: 10.6023/A17120555 Previous Articles     Next Articles

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高效多底物检测与多元分析方法研究进展

叶常青a, 陈硕然a, 李风煜b, 葛婕a, 勇沛怡a, 秦萌b, 宋延林b   

  1. a 苏州科技大学绿色印刷纳米光子工程技术研究中心 江苏省环境功能材料重点实验室 苏州 215009;
    b 中国科学院化学研究所 中国科学院绿色印刷重点实验室 北京 100190
  • 投稿日期:2017-12-26 发布日期:2018-02-26
  • 通讯作者: 李风煜, 宋延林 E-mail:forrest@iccas.ac.cn;ylsong@iccas.ac.cn
  • 作者简介:叶常青,主要从事上转换材料及光子晶体材料应用研究;李风煜,主要从事高效复杂系统分析、聚合物光子晶体与纳米料打印功能器件研究;宋延林,中国科学院化学研究所研究员、博士生导师,中国科学院绿色印刷重点实验室主任.主要从事信息功能材料、纳米功能材料与绿色印刷技术研究.
  • 基金资助:
    项目受江苏省自然科学基金-优秀青年基金(No.BK20170065),江苏省自然科学基金(No.BK20160358);江苏省高校自然科学研究重大项目(No.17KJA430016);江苏省“六大人才高峰”(No.XCL-79);江苏高校“青蓝工程”;国家自然科学基金(Nos.51603141,51473172,51473173)和中科院战略性先导科技专项(No.XDA09020000)资助.

Research Progress of High-performance Multi-analyte Recognitions and Multivariate Analysis

Ye Changqinga, Chen Shuorana, Li Fengyub, Ge Jiea, Yong Peiyia, Qin Mengb, Song Yanlinb   

  1. a Research Center for Green Printing Nanophotonic Materials, Suzhou University of Science and Technology, Jiangsu Key Laboratory for Environmental Functional Materials, Suzhou 215009;
    b Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190
  • Received:2017-12-26 Published:2018-02-26
  • Contact: 10.6023/A17120555 E-mail:forrest@iccas.ac.cn;ylsong@iccas.ac.cn
  • Supported by:
    Project supported by Natural Science Foundation of Jiangsu Province-Excellent Youth Foundation (No. BK20170065), Natural Science Foundation of Jiangsu Province (No. BK20160358), Natural Science Foundation of the Higher Education Institutions of Jiangsu Province (No. 17KJA430016), Six Talent Summits Project of Jiangsu Province (No.XCL-79), Qing Lan Project, the National Natural Science Foundation of China (Nos. 51603141, 51473172, 51473173) and the "Strategic Priority Research Program" of Chinese Academy of Sciences (No. XDA09020000).

The traditional "lock and key" sensor models pursue the "one to one" sensing response for the specific testing and the low limitation of detection, which neglect the practical sample detecting application with multi-analytes and complex contains. Utilizing multi-sensor compounds, the sensor array chip offers multiplex differential sensing response signal to process the multi-analytes discrimination. The critical requirement for successful multi-analyte recognition is to acquire abundant sensing information. However, the "multi to multi" sensor chip needs large numbers of serial probe compounds, which involve com-plicated chemical synthesis and valid compound screening. Inspired by the human sense organ, scientists developed various "cross-reactive" sensor arrays. Here, The recent research progress of multi-analysis and "one to multi" high-efficient detection were introduced. From chemical information excavation, physical signal enhancement, devices integration design, we summarize and forecast the multi-analysis advancement and intelligent sensors.

Key words: multi-analysis, high-performance detection, photonic crystal, sensor array chip, dynamic analysis