Cellulose tris(3, 5-dinitro) benzoate (CTNB) was ultra-sonically synthesized as a reversed Pirkle chiral stationary phase (CSP) type I. After coating on macroporous silica gel, the chiral separation ability was studied as HPLC CSP. The resolution of ibuprofenum was performed with γ=1.25, the resolution of an esfenvalerate intermediate was also achieved (γ=1.39). The mechanism and model of separation were discussed.

Key words: APPLICATION, PREPARATION, BENZOIC ETHER, CELLULOSE, FENVALERATE, IBUPROFEN, MESOTOMY