A Glucose-Selective Surface Plasmon Resonance Sensor Based on Self-assembled Multilayers

Acta Chimica Sinica ›› 2007, Vol. 65 ›› Issue (12): 1185-1189. Previous Articles

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基于自组装多层膜的葡萄糖表面等离子体共振传感器

羊小海, 黎振华, 王青, 王柯敏*

(湖南大学化学生物传感与计量学国家重点实验室生物医学工程中心
生物纳米与分子工程湖南省重点实验室长沙 410082)

投稿日期:2006-10-09 修回日期:2007-01-14 发布日期:2007-06-28
通讯作者: 王柯敏

A Glucose-Selective Surface Plasmon Resonance Sensor Based on Self-assembled Multilayers

YANG Xiao-Hai; LI Zhen-Hua; WANG Qing; WANG Ke-Min*

(State Key Laboratory of Chemo/Biosensing and Chemometrics, Biomedical Engineering Center, Hunan University; Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082)

Received:2006-10-09 Revised:2007-01-14 Published:2007-06-28
Contact: WANG Ke-Min

Abstract

A glucose-selective surface plasmon resonance sensor was constructed by using specific interaction between concanavalin A and sugars. The sensing element was self-assembled multilayers of concanavalin A and dextran formed on gold film. In the presence of glucose, the self-assembled multilayers were disintegrated. As a result, the surface plasmon resonance signal was changed evidently. The signal changes were correlative to the concentration of glucose. The results showed that this sensor could detect the glucose selectively in the range of 0.1～50 mmol•L^－1, and the sensing element could be regenerated for several times.

Key words: surface plasmon resonance, concanavalin A, dextran, glucose

Cite this article

YANG Xiao-Hai; LI Zhen-Hua; WANG Qing; WANG Ke-Min*. A Glucose-Selective Surface Plasmon Resonance Sensor Based on Self-assembled Multilayers[J]. Acta Chimica Sinica, 2007, 65(12): 1185-1189.

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基于自组装多层膜的葡萄糖表面等离子体共振传感器

A Glucose-Selective Surface Plasmon Resonance Sensor Based on Self-assembled Multilayers

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