有机化学 ›› 2023, Vol. 43 ›› Issue (7): 2304-2312.DOI: 10.6023/cjoc202301010 上一篇    下一篇

综述与进展

含碳氟类底物参与的羰基化反应研究进展

安大列a,b, 包志鹏a, 吴小锋a,b,*()   

  1. a中国科学院大连物理化学研究所 大连 116023
    b中国科学院大学 北京 101408
  • 收稿日期:2023-01-09 修回日期:2023-02-03 发布日期:2023-03-07
  • 通讯作者: 吴小锋

Progresses on Fluorocarbon-Containing Substrates Involved Carbonylation Reactions

Da-Lie Ana,b, Zhi-Peng Baoa, Xiao-Feng Wua,b()   

  1. aDalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023
    bUniversity of Chinese Academy of Sciences, Beijing 101408
  • Received:2023-01-09 Revised:2023-02-03 Published:2023-03-07
  • Contact: Xiao-Feng Wu

含氟有机分子的合成和转化已蓬勃发展成为氟化学重要的前沿课题之一, 它深刻地影响着生命科学和材料科学. 其中碳氟化合物参与的羰基化反应是近几年发展起来的一类羰基化反应, 它拥有诸多的挑战. 介绍了过渡金属钯、镍和铜催化的碳氟化合物参与的羰基化反应研究进展. 为了理解这些反应的历程, 也选择了一些具有代表性的反应介绍其反应机理.

关键词: 碳氟化合物, 羰基化反应

The synthesis and transformation of fluorine-containing organic molecules has experienced vigorously development and has become one of the most important frontier topics of fluorine chemistry, which profoundly affects life science and material science. Among them, carbonylative transformation of fluorocarbon-containing substrates is a carbonylation reaction developed in recent years which still has many challenges. This review summarized the progresses on fluorocarbon-containing substrates carbonylation reactions based on transition metal palladium, nickel and copper catalysis. In order to understand the mechanism of these reactions, representative reactions were selected for detailed discussion.

Key words: fluorocarbon, carbonylation reaction