有机化学 ›› 2010, Vol. 30 ›› Issue (05): 640-647. 上一篇    下一篇

综述与进展

介孔二氧化硅纳米粒子应用于可控药物传输系统的若干新进展

袁丽,王蓓娣,唐倩倩,张晓鸿,张晓环,杨东,胡建华*   

  1. (复旦大学高分子科学系 聚合物分子工程教育部重点实验室 先进材料实验室 上海 200433)
  • 收稿日期:2009-08-28 修回日期:2009-10-07 出版日期:2010-05-25 发布日期:2009-11-06
  • 通讯作者: 胡建华 E-mail:hujh@fudan.edu.cn

New Progress in the Applications of Mesoporous Silica Nanoparticles to Controlled Drug Delivery System

YUAN Li, WANG Bei-Di, TANG Qian-Qian, ZHANG Xiao-Hong, ZHANG Xiao-Huan, YANG Dong, HU Jian-Hua   

  1. (Key Laboratory of Molecular Engineering of Polymers of Ministry of Education & Laboratory of Advanced Materials, Department of Macromolecular Science, Fudan University, Shanghai 200433)
  • Received:2009-08-28 Revised:2009-10-07 Online:2010-05-25 Published:2009-11-06

通过对介孔二氧化硅纳米粒子(MSN)载药机理、药物控释机理和靶向方法的介绍, 对MSN在可控药物传输系统中的应用加以综述.

关键词: 介孔二氧化硅纳米粒子, 药物传输, 控制释放, 靶向

Through the introduction of drug loading mechanism, drug controlled release mechanism, and targeting methods of mesoporous silica nanoparticles (MSN), the application of MSN to controlled drug delivery system is reviewed.

Key words: mesoporous silica nanoparticle, drug delivery, controlled release, targeting