有机化学 ›› 2008, Vol. 28 ›› Issue (09): 1515-1522. 上一篇    下一篇

综述与进展

季戊四醇衍生物为骨架的糖簇、糖树枝状分子的合成与应用

张华承 ; 郝爱友*; 杜光焰 ; 申 健   

  1. 山东大学化学与化工学院 济南 250100
  • 收稿日期:2007-12-12 修回日期:2007-12-25 发布日期:2008-09-20
  • 通讯作者: 郝爱友

Synthesis and Application of Glycocluster and Glycodendrimer with Pentaerythritol Derivatives as Scaffolds

ZHANG, Hua-Cheng; HAO, Ai-You* ; DU, Guang-Yan; SHEN, Jian   

  1. School of Chemistry & Chemical Engineering, Shandong University, Jinan 250100
  • Received:2007-12-12 Revised:2007-12-25 Published:2008-09-20
  • Contact: HAO, Ai-You

综述了以季戊四醇衍生物为骨架的糖簇、糖树枝状分子的合成与应用. 由于季戊四醇衍生物本身所具备的结构特点, 这类分子非常适合于合成新型的糖簇分子和糖树枝状分子. 同时, 由于季戊四醇衍生物在有机合成领域应用广泛, 很多有机合成方法都可以应用到这类糖缀合物的合成中.

关键词: 季戊四醇衍生物, 糖簇分子, 多价效应, 糖树枝状分子

The synthesis and application of glycocluster and glycodendrimer with pentaerythritol derivatives as scaffolds are reviewed. It is very suitable for pentaerythritol derivatives to be applied to synthesize new glycocluster and glycodendrimer because of their special structural characters. Owing to the versatile application of pentaerythritol derivatives to organic synthesis, a lot of organic synthesis methods are able to be used in preparation of the new kind of glycoconjugate.

Key words: pentaerythritol derivative, glycodendrimer, multivalent effect, glycocluster