Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (04): 780-791.DOI: 10.6023/cjoc201211023 Previous Articles     Next Articles



毛可彬a, 付晓平b, 刘丹a, 李石b, 刘元红b   

  1. a 沈阳化工大学化学工程学院 沈阳 110142;
    b 中国科学院上海有机化学研究所 金属有机化学国家重点实验室 上海 200032
  • 收稿日期:2012-11-13 修回日期:2012-11-26 发布日期:2012-12-07
  • 通讯作者: 刘丹, 刘元红
  • 基金资助:

    国家自然科学基金(Nos. 21072208, 21125210, 21121062)和国家重点基础研究发展计划(973计划, No. 2011CB808700)资助项目.

Construction of Metallacycles via Zirconium-Benzyne Complexes and Its Application in Organic Synthesis

Mao Kebina, Fu Xiaopingb, Liu Dana, Li Shib, Liu Yuanhongb   

  1. a Colledge of Chemical Engineering, Shenyang University of Chemical Technology, Shenyang 110142;
    b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2012-11-13 Revised:2012-11-26 Published:2012-12-07
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21072208, 21125210, 21121062) and the Major State Basic Research Development Program (973 Program, No. 2011CB808700).

Zirconium-benzyne complex is an important and highly reactive organometallic species. It can react with unsaturated substrates such as alkenes, alkynes, aldehydes, ketones, nitriles etc. to form metallacyles. A large variety of metallacycles can be constructed by modifying the substitution patterns of the substrates, chemical ratio of reactants, different Cp ligands or reaction conditions and so on. These metallacycles are highly useful for further transformations through the reactions with different electrophiles. This review summarizes the synthetic methods of zirconium-benzyne complexes, reactions of zirconium-benzyne complexes with various unsaturated molecules leading to metallacycles, and the applications of these metallacycles in organic chemistry. An outlook of zirconium-benzyne complexes in organic synthesis is also provided at the end of this review.

Key words: zirconium-benzyne, metallacycle, reactivity, coupling reaction