Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (2): 455-470.DOI: 10.6023/cjoc202208008 Previous Articles     Next Articles


马彪a, 章淼淼a, 李占宇a,b,*(), 彭进松a, 陈春霞a,*()   

  1. a 东北林业大学化学化工与资源利用学院 哈尔滨 150040
    b 东北林业大学林业工程博士后流动站 哈尔滨 150040
  • 收稿日期:2022-08-06 修回日期:2022-09-25 发布日期:2022-10-31
  • 基金资助:
    中央高校基本科研业务费专项资金基金(2572020BU03); 中国博士后科学基金(2020M681065); 黑龙江省博士后基金(LBH-Z20103)

Recent Advance of Transition Metal-Free Catalyzed Suzuki-Type Cross Coupling Reaction

Biao Maa, Miaomiao Zhanga, Zhanyu Lia,b(), Jinsong Penga, Chunxia Chena()   

  1. a Chemical Engineering and Resource Utilization, College of Chemistry, Northeast Forestry University, Harbin 150040
    b Material Science and Engineering College, Northeast Forestry University, Harbin 150040
  • Received:2022-08-06 Revised:2022-09-25 Published:2022-10-31
  • Contact: *E-mail:;
  • Supported by:
    Fundamental Research Funds for the Central Universities(2572020BU03); China Postdoctoral Science Foundation Funded Project(2020M681065); Heilongjiang Postdoctoral Fund(LBH-Z20103)

Transition metal catalyzed Suzuki coupling reaction serves as one of the most versatile and widespread methods for the C-C bonds formation, which greatly promotes the development of synthetic chemistry. Currently, the Suzuki coupling reactions heavily rely on noble palladium-catalyzed system. However, the high cost, toxicity and low reserves of palladium have become the main obstacles for their development in organic synthesis. Over the past two decades, metal-free catalyzed Suzuki-Type cross coupling reactions earned extensive concern, and a large number of efficient and new reaction systems have been reported. In this review, the recent progresses of metal-free catalyzed Suzuki-Type cross coupling reactions are summarized, mainly including bases, organometallic reagents and organic molecules promoted reactions. In addition, the mechanism of reaction is also discussed in this review.

Key words: metal-free catalysis, Suzuki cross-coupling, organic synthesis, base promoting, coupling reaction